PPEF1 Antibody

Product Specifications

Background

This gene encodes a member of the serine/threonine protein phosphatase with EF-hand motif family. The protein contains a protein phosphatase catalytic domain, and at least two EF-hand calcium-binding motifs in its C terminus. Although its substrate (s) is unknown, the encoded protein has been suggested to play a role in specific sensory neuron function and/or development. This gene shares high sequence similarity with the Drosophila retinal degeneration C (rdgC) gene. Several alternatively spliced transcript variants, each encoding a distinct isoform, have been described.

NCBI Gene ID

5475

Swiss Prot

O14829

Accession Number

O14829

Host

Rabbit

Reactivity

Human

Immunogen

This PPEF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 298-327 amino acids from the Central region of human PPEF1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

76 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PPEF1

NCBI Official Name

Serine/threonine-protein phosphatase with EF-hands 1

NCBI Organism

Homo sapiens

Background Reference 01

Ross, M.T., et al. Nature 434 (7031) :325-337 (2005)

Background Reference 02

Hillman, R.T., et al. Genome Biol. (2), R8 (2004) :

Background Reference 03

Gevaert, K., et al. Nat. Biotechnol. 21 (5) :566-569 (2003)

Background Reference 04

Kutuzov, M.A., et al. Biochem. Biophys. Res. Commun. 293 (3) :1047-1052 (2002)

Other Product Names

Serine/threonine-protein phosphatase with EF-hands 1, PPEF-1, Protein phosphatase with EF calcium-binding domain, PPEF, Serine/threonine-protein phosphatase 7, PP7, PPEF1, PPEF, PPP7C