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RNF40 Antibody

Product Specifications

Background

The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery.

NCBI Gene ID

9810

Swiss Prot

O75150

Accession Number

O75150

Host

Rabbit

Reactivity

Human

Immunogen

This RNF40 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 697-725 amino acids from the C-terminal region of human RNF40.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

114 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

RNF40

NCBI Official Name

E3 ubiquitin-protein ligase BRE1B

NCBI Organism

Homo sapiens

Background Reference 01

Chernikova, S.B., et al. Radiat. Res. 174 (5) :558-565 (2010)

Background Reference 02

Kim, J., et al. Cell 137 (3) :459-471 (2009)

Background Reference 03

Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

Background Reference 04

Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

Other Product Names

E3 ubiquitin-protein ligase BRE1B, BRE1-B, 632-, 95 kDa retinoblastoma-associated protein, RBP95, RING finger protein 40, RNF40, BRE1B, KIAA0661

Tested Applications

WB

Physical Properties

Liquid

Curated Selection

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