OTU7B Antibody

Product Specifications

Background

OTU7B has deubiquitinating activity that is directed towards 'Lys-48' or 'Lys-63'-linked polyubiquitin chains. Hydrolyzes both linear and branched forms of polyubiquitin. Negative regulator of nuclear factor NF-kappa-B.

NCBI Gene ID

56957

Swiss Prot

Q6GQQ9

Accession Number

Q6GQQ9

Host

Rabbit

Reactivity

Human

Immunogen

This OTU7B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 757-784 amino acids from the C-terminal region of human OTU7B.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

93 kDa

Fragment

Rabbit Ig

Symbol

OTUD7B

NCBI Official Name

OTU domain-containing protein 7B

NCBI Organism

Homo sapiens

Background Reference 01

Bremm, A., et al. Nat. Struct. Mol. Biol. 17 (8) :939-947 (2010)

Background Reference 02

Jin, Z., et al. Cell 137 (4) :721-735 (2009)

Background Reference 03

Enesa, K., et al. J. Biol. Chem. 283 (27) :18582-18590 (2008)

Background Reference 04

Bohgaki, M., et al. Biochim. Biophys. Acta 1783 (5) :826-837 (2008)

Other Product Names

OTU domain-containing protein 7B, Cellular zinc finger anti-NF-kappa-B protein, Zinc finger A20 domain-containing protein 1, Zinc finger protein Cezanne, OTUD7B, ZA20D1