Mouse Pdk3 Antibody

Product Specifications

Background

Pdk3 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism (By similarity) .

NCBI Gene ID

236900

Swiss Prot

Q922H2

Accession Number

Q922H2

Host

Rabbit

Reactivity

Mouse

Immunogen

This Mouse Pdk3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 387-414 amino acids from the C-terminal region of mouse Pdk3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

48 kDa

Fragment

Rabbit Ig

Symbol

Pdk3

NCBI Official Name

[Pyruvate dehydrogenase (acetyl-transferring) ] kinase isozyme 3, mitochondrial

NCBI Organism

Mus musculus

Background Reference 01

Pagliarini, D.J., et al. Cell 134 (1) :112-123 (2008)

Background Reference 02

Blackshaw, S., et al. PLoS Biol. (9), E247 (2004) :

Background Reference 03

Visel, A., et al. Nucleic Acids Res. 32 (DATABASE ISSUE), D552-D556 (2004) :

Background Reference 04

Mootha, V.K., et al. Cell 115 (5) :629-640 (2003)

Other Product Names

[Pyruvate dehydrogenase (acetyl-transferring) ] kinase isozyme 3, mitochondrial, Pyruvate dehydrogenase kinase isoform 3, Pdk3

Tested Applications

WB, IHC-P

Physical Properties

Liquid

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