Mouse Mapk3 Antibody

Product Specifications

Background

Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2) and heat shock factor protein 4 (HSF4) (By similarity) . Phosphorylates SPZ1.

NCBI Gene ID

26417

Swiss Prot

Q63844

Accession Number

Q63844

Host

Rabbit

Reactivity

Mouse

Immunogen

This Mouse Mapk3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 353-380 amino acids from the C-terminal region of mouse Mapk3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

43 kDa

Fragment

Rabbit Ig

Symbol

Mapk3

NCBI Official Name

Mitogen-activated protein kinase 3

NCBI Organism

Mus musculus

Background Reference 01

Chen, W., et al. Biochem. Biophys. Res. Commun. 401 (3) :339-343 (2010)

Background Reference 02

Chandrakesan, P., et al. J. Biol. Chem. 285 (43) :33485-33498 (2010)

Background Reference 03

Alter, B.J., et al. J. Neurosci. 30 (34) :11537-11547 (2010)

Background Reference 04

Spruce, T., et al. Dev. Cell 19 (2) :207-219 (2010)

Other Product Names

Mitogen-activated protein kinase 3, MAP kinase 3, MAPK 3, ERT2, Extracellular signal-regulated kinase 1, ERK-1, Insulin-stimulated MAP2 kinase, MAP kinase isoform p44, p44-MAPK, MNK1, Microtubule-associated protein 2 kinase, p44-ERK1, Mapk3, Erk1, Prkm3