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Mouse Map3k3 Antibody

Product Specifications

Background

Component of a protein kinase signal transduction cascade. Map3k3 mediates activation of the NF-kappa-B, AP1 and DDIT3 transcriptional regulators.

NCBI Gene ID

26406

Swiss Prot

Q61084

Accession Number

Q61084

Host

Rabbit

Reactivity

Mouse

Immunogen

This Mouse Map3k3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-257 amino acids from the Central region of mouse Map3k3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

71 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

Map3k3

NCBI Official Name

Mitogen-activated protein kinase kinase kinase 3

NCBI Organism

Mus musculus

Background Reference 01

Zhang, J., et al. J. Immunol. 185 (6) :3554-3563 (2010)

Background Reference 02

Yu, L., et al. Cancer Res. 70 (4) :1334-1343 (2010)

Background Reference 03

Sun, W., et al. Cell. Signal. 21 (10) :1488-1494 (2009)

Background Reference 04

Retting, K.N., et al. Development 136 (7) :1093-1104 (2009)

Other Product Names

Mitogen-activated protein kinase kinase kinase 3, MAPK/ERK kinase kinase 3, MEK kinase 3, MEKK 3, Map3k3, Mekk3

Tested Applications

WB

Physical Properties

Liquid

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