DRAGON Antibody
Product Specifications
Background
Repulsive Guidance Molecule B (RGMB) is primarily expressed in the central nervous system. RGM A and B both appear at every level of the developing neural axis, where they colocalize to a large extent in the mantle layer, although only RGMA appears in the neuroepithelium, and only RGMB in the peripheral nervous system. During development, both RGMA and B appear also in lung and in limb cartilage, while RGMB has additional expression domains in pancreas.
NCBI Gene ID
285704
Swiss Prot
Q6NW40
Accession Number
Q6NW40
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This DRAGON (RGMB) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 376-406 amino acids from the C-terminal region of human DRAGON (RGMB) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein G column, followed by dialysis against PBS.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=57-567
Calculated Molecular Weight
48 kDa
Fragment
Rabbit Ig
Symbol
RGMB
NCBI Official Name
RGM domain family member B
NCBI Organism
Homo sapiens
Background Reference 01
Schnichels, S., Gene Expr. Patterns (1), 1-11 (2007)
Background Reference 02
Metzger, M., Dev. Dyn. 234 (1), 169-175 (2005)
Background Reference 03
Xia, Y., Endocrinology 146 (8), 3614-3621 (2005)
Other Product Names
RGM domain family member B, DRG11-responsive axonal guidance and outgrowth of neurite, DRAGON, RGMB
Tested Applications
WB, IHC-P
Protein ID
327478562
Physical Properties
Liquid
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