PRSS8 Antibody

Product Specifications

Background

This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is highly expressed in prostate epithelia and is one of several proteolytic enzymes found in seminal fluid. The proprotein is cleaved to produce a light chain and a heavy chain which are associated by a disulfide bond. It is active on peptide linkages involving the carboxyl group of lysine or arginine.

NCBI Gene ID

5652

Swiss Prot

Q16651

Accession Number

Q16651

Host

Rabbit

Reactivity

Human

Immunogen

This PRSS8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 190-219 amino acids from the Central region of human PRSS8.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

36 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PRSS8

NCBI Official Name

Prostasin

NCBI Organism

Homo sapiens

Background Reference 01

Chen, Y.W., et al. J. Biol. Chem. 285 (41) :31755-31762 (2010)

Background Reference 02

Chen, M., et al. Mol. Cell. Biochem. 337 (1-2), 259-266 (2010) :

Background Reference 03

Fu, Y.Y., et al. Hum. Reprod. 25 (3) :623-632 (2010)

Background Reference 04

Ko, T., et al. J. Biomed. Biotechnol. 2010, 793843 (2010) :

Other Product Names

Prostasin, 3421-, Channel-activating protease 1, CAP1, Serine protease 8, Prostasin light chain, Prostasin heavy chain, PRSS8

Tested Applications

Protein ID

2833277

Physical Properties

Liquid

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