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HSF1 Antibody

Product Specifications

Background

The product of this gene is a heat-shock transcription factor. Transcription of heat-shock genes is rapidly induced after temperature stress. Hsp90, by itself and/or associated with multichaperone complexes, is a major repressor of this gene.

NCBI Gene ID

3297

Swiss Prot

Q00613

Accession Number

Q00613

Host

Rabbit

Reactivity

Human

Immunogen

This HSF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-100 amino acids from the N-terminal region of human HSF1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Xenopus

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

57 kDa

Fragment

Rabbit Ig

Symbol

HSF1

NCBI Official Name

Heat shock factor protein 1

NCBI Organism

Homo sapiens

Background Reference 01

Hayashida, N., et al. EMBO J. 29 (20) :3459-3469 (2010)

Background Reference 02

Sangle, G.V., et al. Endocrinology 151 (9) :4455-4466 (2010)

Background Reference 03

Shunmei, E., et al. Mol. Cells 29 (5) :527-531 (2010)

Background Reference 04

Kim, S.A., et al. Int. J. Oncol. 36 (4) :867-872 (2010)

Other Product Names

Heat shock factor protein 1, HSF 1, Heat shock transcription factor 1, HSTF 1, HSF1, HSTF1

Tested Applications

WB, IHC-P

Protein ID

462333

Physical Properties

Liquid

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