MEF2D Antibody
Product Specifications
Background
MEF2D is a transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT] (4) TAR-3', found in numerous muscle-specific, growth factor-and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. Plays a critical role in the regulation of neuronal apoptosis (By similarity) .
NCBI Gene ID
4209
Swiss Prot
Q14814
Accession Number
Q14814
Host
Rabbit
Reactivity
Human
Immunogen
This MEF2D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 251-279 amino acids from the Central region of human MEF2D.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
56 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
MEF2D
NCBI Official Name
Myocyte-specific enhancer factor 2D
NCBI Organism
Homo sapiens
Background Reference 01
Jablonski, K.A., et al. Diabetes 59 (10) :2672-2681 (2010)
Background Reference 02
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 03
Aude-Garcia, C., et al. Biochem. J. 430 (2) :237-244 (2010)
Background Reference 04
Czubryt, M.P., et al. J. Biol. Chem. 285 (22) :16942-16950 (2010)
Other Product Names
Myocyte-specific enhancer factor 2D, MEF2D
Tested Applications
WB
Protein ID
2500876
Physical Properties
Liquid
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