Mouse Map2k1 Antibody

Product Specifications

Background

Map2k1 catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates ERK1 and ERK2 MAP kinases.

NCBI Gene ID

26395

Swiss Prot

P31938

Accession Number

P31938

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This Mouse Map2k1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 269-296 amino acids from the C-terminal region of mouse Map2k1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Hamster, Rabbit, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

43 kDa

Fragment

Rabbit Ig

Symbol

Map2k1

NCBI Official Name

Dual specificity mitogen-activated protein kinase kinase 1

NCBI Organism

Mus musculus

Background Reference 01

Chandrakesan, P., et al. J. Biol. Chem. 285 (43) :33485-33498 (2010)

Background Reference 02

Yang, T., et al. J. Clin. Invest. 120 (7) :2474-2485 (2010)

Background Reference 03

Cho, K.W., et al. J. Exp. Zool.Mol. Dev. Evol. 312 (8) :901-911 (2009)

Background Reference 04

Jo, C., et al. Cell. Signal. 21 (12) :1910-1917 (2009)

Other Product Names

Dual specificity mitogen-activated protein kinase kinase 1, MAP kinase kinase 1, MAPKK 1, ERK activator kinase 1, MAPK/ERK kinase 1, MEK 1, Map2k1, Mek1, Prkmk1