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STAM2 Antibody

Product Specifications

Background

The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM) . Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation.

NCBI Gene ID

10254

Swiss Prot

O75886

Accession Number

O75886

Host

Rabbit

Reactivity

Human

Immunogen

This STAM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 143-172 amino acids from the Central region of human STAM2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

58 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

STAM2

NCBI Official Name

Signal transducing adapter molecule 2

NCBI Organism

Homo sapiens

Background Reference 01

Stuible, M., et al. J. Biol. Chem. 285 (31) :23899-23907 (2010)

Background Reference 02

Rismanchi, N., et al. Traffic 10 (2) :201-217 (2009)

Background Reference 03

Venkatesan, K., et al. Nat. Methods 6 (1) :83-90 (2009)

Background Reference 04

Kong, C., et al. J. Biol. Chem. 282 (20) :15294-15301 (2007)

Other Product Names

Signal transducing adapter molecule 2, STAM-2, Hrs-binding protein, STAM2, HBP

Tested Applications

WB

Physical Properties

Liquid

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