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ODC1 Antibody

Product Specifications

Background

This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter.

NCBI Gene ID

4953

Swiss Prot

P11926

Accession Number

P11926

Host

Rabbit

Reactivity

Human

Immunogen

This ODC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 323-352 amino acids from the C-terminal region of human ODC1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=57-425

Calculated Molecular Weight

51 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ODC1

NCBI Official Name

Ornithine decarboxylase

NCBI Organism

Homo sapiens

Background Reference 01

Chaturvedi, R., et al. Gastroenterology 139 (5) :1686-1698 (2010)

Background Reference 02

Zell, J.A., et al. J. Natl. Cancer Inst. 102 (19) :1513-1516 (2010)

Background Reference 03

Geerts, D., et al. Int. J. Cancer 126 (9) :2012-2024 (2010)

Background Reference 04

Hughes, D., et al. Colorectal Dis (2010) In press :

Other Product Names

Ornithine decarboxylase, ODC, ODC1

Tested Applications

WB

Protein ID

118377

Physical Properties

Liquid

Curated Selection

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