PPCDC Antibody
Product Specifications
Background
Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is an essential universal pathway in prokaryotes and eukaryotes. PPCDC (EC 4.1.1.36), one of the last enzymes in this pathway, converts phosphopantothenoylcysteine to 4-prime-phosphopantetheine (Daugherty et al., 2002 [PubMed 11923312]) .
NCBI Gene ID
60490
Swiss Prot
Q96CD2
Accession Number
Q96CD2
Host
Rabbit
Reactivity
Mouse
Immunogen
This PPCDC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-66 amino acids from the N-terminal region of human PPCDC.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
22 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PPCDC
NCBI Official Name
Phosphopantothenoylcysteine decarboxylase
NCBI Organism
Homo sapiens
Background Reference 01
Strauss, E., et al. Biochemistry 43 (49) :15520-15533 (2004)
Background Reference 02
Manoj, N., et al. Acta Crystallogr.Biol. Crystallogr. 59 (PT 10), 1762-1766 (2003) :
Background Reference 03
Daugherty, M., et al. J. Biol. Chem. 277 (24) :21431-21439 (2002)
Other Product Names
Phosphopantothenoylcysteine decarboxylase, PPC-DC, CoaC, PPCDC, COAC
Tested Applications
WB
Protein ID
296434457
Physical Properties
Liquid
Curated Selection
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