ERG25 Antibody
Product Specifications
Background
Sterol-C4-mehtyl oxidase-like protein was isolated based on its similarity to the yeast ERG25 protein. It contains a set of putative metal binding motifs with similarity to that seen in a family of membrane desaturases-hydroxylases. The protein is localized to the endoplasmic reticulum membrane and is believed to function in cholesterol biosynthesis. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
NCBI Gene ID
6307
Swiss Prot
Q15800
Accession Number
Q15800
Host
Rabbit
Reactivity
Human
Immunogen
This ERG25 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 264-293 amino acids from the C-terminal region of human ERG25.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
35 kDa
Fragment
Rabbit Ig
Symbol
MSMO1
NCBI Official Name
Methylsterol monooxygenase 1
NCBI Organism
Homo sapiens
Background Reference 01
Lu, Y., et al. J. Lipid Res. 49 (12) :2582-2589 (2008)
Background Reference 02
Lim, J., et al. Cell 125 (4) :801-814 (2006)
Background Reference 03
Li, L., et al. J. Biol. Chem. 271 (28) :16927-16933 (1996)
Other Product Names
Methylsterol monooxygenase 1, C-4 methylsterol oxidase, MSMO1, DESP4, ERG25, SC4MOL
Tested Applications
WB, IHC-P
Protein ID
2498340
Physical Properties
Liquid
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