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Mouse Map3k7 Antibody

Product Specifications

Background

Component of a protein kinase signal transduction cascade. Mediator of TRAF6 and TGF-beta signal transduction. Activates IKBKB and MAPK8 in response to TRAF6 signaling. Stimulates NF-kappa-B activation and the p38 MAPK pathway. In osmotic stress signaling, plays a major role in the activation of MAPK8/JNK, but not that of NF-kappa-B.

NCBI Gene ID

26409

Swiss Prot

Q62073

Accession Number

Q62073

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This Mouse Map3k7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 131-160 amino acids from the N-terminal region of mouse Map3k7.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Immunology, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=57-351

Calculated Molecular Weight

64 kDa

Fragment

Rabbit Ig

Symbol

Map3k7

NCBI Official Name

Mitogen-activated protein kinase kinase kinase 7

NCBI Organism

Mus musculus

Background Reference 01

Kajino-Sakamoto, R., et al. J. Immunol. 185 (8) :4729-4737 (2010)

Background Reference 02

Wu, Z.H., et al. Mol. Cell 40 (1) :75-86 (2010)

Background Reference 03

Scholz, R., et al. J. Biol. Chem. 285 (33) :25753-25766 (2010)

Background Reference 04

Greenblatt, M.B., et al. J. Clin. Invest. 120 (7) :2457-2473 (2010)

Other Product Names

Mitogen-activated protein kinase kinase kinase 7, Transforming growth factor-beta-activated kinase 1, TGF-beta-activated kinase 1, Map3k7, Tak1

Tested Applications

WB, IHC-P

Physical Properties

Liquid

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