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Mouse Acvr2b Antibody

Product Specifications

Background

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A.

NCBI Gene ID

11481

Swiss Prot

P27040

Accession Number

P27040

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This Mouse Acvr2b antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 148-176 amino acids from the Central region of mouse Acvr2b.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

61 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

Acvr2b

NCBI Official Name

Activin receptor type-2B

NCBI Organism

Mus musculus

Background Reference 01

Natale, D.R., et al. Dev. Biol. 335 (1) :120-131 (2009)

Background Reference 02

Gamer, L.W., et al. Dev. Dyn. 238 (9) :2374-2381 (2009)

Background Reference 03

Yamamoto, M., et al. J. Cell Biol. 184 (2) :323-334 (2009)

Background Reference 04

Morita, S., et al. PLoS ONE (1), E4212 (2009) :

Other Product Names

Activin receptor type-2B, Activin receptor type IIB, ACTR-IIB, Acvr2b

Tested Applications

WB

Physical Properties

Liquid

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