KCNC2 Antibody

Product Specifications

Background

The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to one of these subfamilies, namely the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. Three transcript variants encoding three different isoforms have been found for this gene.

NCBI Gene ID

3747

Swiss Prot

Q96PR1

Accession Number

Q96PR1

Host

Rabbit

Reactivity

Mouse

Immunogen

This KCNC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 544-573 amino acids from the C-terminal region of human KCNC2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

70 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

KCNC2

NCBI Official Name

Potassium voltage-gated channel subfamily C member 2

NCBI Organism

Homo sapiens

Background Reference 01

Wang, Z., et al. J. Gen. Physiol. 133 (4) :361-374 (2009)

Background Reference 02

Gutman, G.A., et al. Pharmacol. Rev. 57 (4) :473-508 (2005)

Background Reference 03

Haas, M., et al. Mamm. Genome 4 (12) :711-715 (1993)

Other Product Names

Potassium voltage-gated channel subfamily C member 2, Voltage-gated potassium channel Kv32, KCNC2

Tested Applications

Protein ID

74752079

Physical Properties

Liquid

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