GUCA2A Antibody

Product Specifications

Background

Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins.

NCBI Gene ID

2980

Swiss Prot

Q02747

Accession Number

Q02747

Host

Rabbit

Reactivity

Human

Immunogen

This GUCA2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-54 amino acids from the Central region of human GUCA2A.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

12 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

GUCA2A

NCBI Official Name

Guanylin

NCBI Organism

Homo sapiens

Background Reference 01

Dell'Orco, D., et al. Cell. Mol. Life Sci. 67 (6) :973-984 (2010)

Background Reference 02

Chen, Y.B., et al. Zhonghua Wei Chang Wai Ke Za Zhi 12 (5) :515-517 (2009)

Background Reference 03

Albano, F., et al. Pediatr. Res. 58 (1) :159-163 (2005)

Background Reference 04

Sindic, A., et al. Kidney Int. 67 (4) :1420-1427 (2005)

Other Product Names

Guanylin, Guanylate cyclase activator 2A, Guanylate cyclase-activating protein 1, Guanylate cyclase-activating protein I, GCAP-I, HMW-guanylin, Guanylin, GUCA2A, GUCA2