ARHGAP24 Antibody

Product Specifications

Background

ARHGAPs, such as ARHGAP24, encode negative regulators of Rho GTPases (see ARHA; MIM 165390), which are implicated in actin remodeling, cell polarity, and cell migration (Katoh and Katoh, 2004 [PubMed 15254788]) .

NCBI Gene ID

83478

Swiss Prot

Q8N264

Accession Number

Q8N264

Host

Rabbit

Reactivity

Human

Immunogen

This ARHGAP24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 587-616 amino acids from the C-terminal region of human ARHGAP24.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

84 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ARHGAP24

NCBI Official Name

Rho GTPase-activating protein 24

NCBI Organism

Homo sapiens

Background Reference 01

Horinouchi, M., et al. Pediatr Hematol Oncol 27 (5) :344-354 (2010)

Background Reference 02

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 03

Holm, H., et al. Nat. Genet. 42 (2) :117-122 (2010)

Background Reference 04

Pfeufer, A., et al. Nat. Genet. 42 (2) :153-159 (2010)

Other Product Names

Rho GTPase-activating protein 24, Filamin-A-associated RhoGAP, FilGAP, RAC1- and CDC42-specific GTPase-activating protein of 72 kDa, RC-GAP72, Rho-type GTPase-activating protein 24, RhoGAP of 73 kDa, Sarcoma antigen NY-SAR-88, p73RhoGAP, ARHGAP24, FILGAP