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TRPC5 Antibody

Product Specifications

Background

This gene belongs to the transient receptor family. It encodes one of the seven mammalian TRPC (transient receptor potential channel) proteins. The encoded protein is a multi-pass membrane protein and is thought to form a receptor-activated non-selective calcium permeant cation channel. The protein is active alone or as a heteromultimeric assembly with TRPC1, TRPC3, and TRPC4. It also interacts with multiple proteins including calmodulin, CABP1, enkurin, Na (+) -H+ exchange regulatory factor (NHERF), interferon-induced GTP-binding protein (MX1), ring finger protein 24 (RNF24), and SEC14 domain and spectrin repeat-containing protein 1 (SESTD1) .

NCBI Gene ID

7224

Swiss Prot

Q9UL62

Accession Number

Q9UL62

Host

Rabbit

Reactivity

Human

Immunogen

This TRPC5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 254-283 amino acids from the N-terminal region of human TRPC5.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rabbit

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

111 kDa

Fragment

Rabbit Ig

Symbol

TRPC5

NCBI Official Name

Short transient receptor potential channel 5

NCBI Organism

Homo sapiens

Background Reference 01

Al-Shawaf, E., et al. Arterioscler. Thromb. Vasc. Biol. 30 (7) :1453-1459 (2010)

Background Reference 02

Wong, C.O., et al. Pflugers Arch. 460 (1) :121-130 (2010)

Background Reference 03

Miehe, S., et al. J. Biol. Chem. 285 (16) :12426-12434 (2010)

Background Reference 04

Gross, S.A., et al. J. Biol. Chem. 284 (49) :34423-34432 (2009)

Other Product Names

Short transient receptor potential channel 5, TrpC5, Transient receptor protein 5, TRP-5, hTRP-5, hTRP5, TRPC5, TRP5

Tested Applications

WB, IHC-P

Protein ID

10720321

Physical Properties

Liquid

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