CTAG2 Antibody

Product Specifications

Background

This gene encodes an autoimmunogenic tumor antigen that belongs to the ESO/LAGE family of cancer-testis antigens. This protein is expressed in a wide array of cancers including melanoma, breast cancer, bladder cancer and prostate cancer. This protein is also expressed in normal testis tissue. An alternative open reading frame product of this gene has been described in PMID 10399963. This alternate protein, termed CAMEL, is a tumor antigen that is recognized by melanoma-specific cytotoxic T-lymphocytes. Alternate splicing results in multiple transcript variants. [provided by RefSeq].

NCBI Gene ID

30848

Swiss Prot

O75638

Accession Number

O75638

Host

Rabbit

Reactivity

Human

Immunogen

This CTAG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 122-149 amino acids from the Central region of human CTAG2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

21 kDa

Fragment

Rabbit Ig

Symbol

CTAG2

NCBI Official Name

Cancer/testis antigen 2

NCBI Organism

Homo sapiens

Background Reference 01

Wang, X.Y., et al. Oncol. Rep. 21 (3) :713-719 (2009)

Background Reference 02

Shao, Y., et al. J. Cancer Res. Clin. Oncol. 134 (4) :495-502 (2008)

Background Reference 03

Andrade, V.C., et al. Cancer Immun. 8, (2008) :

Background Reference 04

Kan, T., et al. Oncology 70 (1) :25-33 (2006)

Other Product Names

Cancer/testis antigen 2, CT2, Autoimmunogenic cancer/testis antigen NY-ESO-2, Cancer/testis antigen 62, CT62, L antigen family member 1, LAGE-1, CTAG2, ESO2, LAGE1