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H1FX Antibody

Product Specifications

Background

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a member of the histone H1 family.

NCBI Gene ID

8971

Swiss Prot

Q92522

Accession Number

Q92522

Host

Rabbit

Reactivity

Human

Immunogen

This H1FX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-167 amino acids from the C-terminal region of human H1FX.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

22 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

H1FX

NCBI Official Name

Histone H1x

NCBI Organism

Homo sapiens

Background Reference 01

Warneboldt, J., et al. BMC Cancer 8, 388 (2008) :

Background Reference 02

Stoldt, S., et al. Biol. Cell 99 (10) :541-552 (2007)

Background Reference 03

Takata, H., et al. FEBS Lett. 581 (20) :3783-3788 (2007)

Background Reference 04

Sugiyama, N., et al. Mol. Cell Proteomics 6 (6) :1103-1109 (2007)

Other Product Names

Histone H1x, H1FX

Tested Applications

WB

Protein ID

6016184

Physical Properties

Liquid

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