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DOLPP1 Antibody

Product Specifications

Background

DOLPP1 is required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate (By similarity) .

NCBI Gene ID

57171

Swiss Prot

Q86YN1

Accession Number

Q86YN1

Host

Rabbit

Reactivity

Mouse

Immunogen

This DOLPP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 207-236 amino acids from the C-terminal region of human DOLPP1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

27 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

DOLPP1

NCBI Official Name

Dolichyldiphosphatase 1

NCBI Organism

Homo sapiens

Background Reference 01

Humphray, S.J., et al. Nature 429 (6990) :369-374 (2004)

Background Reference 02

Rush, J.S., et al. J. Biol. Chem. 277 (47) :45226-45234 (2002)

Background Reference 03

Gilley, J., et al. Hum. Mol. Genet. 8 (7) :1313-1320 (1999)

Background Reference 04

Wedgwood, J.F., et al. J. Biol. Chem. 255 (3) :1120-1123 (1980)

Other Product Names

Dolichyldiphosphatase 1, Dolichyl pyrophosphate phosphatase 1, DOLPP1, LSFR2

Tested Applications

WB

Protein ID

45476905

Physical Properties

Liquid

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