USP40 Antibody

Product Specifications

Background

Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP40 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]) .

NCBI Gene ID

55230

Swiss Prot

Q9NVE5

Accession Number

Q9NVE5

Host

Rabbit

Reactivity

Mouse

Immunogen

This USP40 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-91 amino acids from the N-terminal region of human USP40.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

140 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

USP40

NCBI Official Name

Ubiquitin carboxyl-terminal hydrolase 40

NCBI Organism

Homo sapiens

Background Reference 01

Wu, Y.R., et al. Clin. Chim. Acta 411 (13-14), 955-958 (2010) :

Background Reference 02

Li, Y., et al. Hum. Mutat. 27 (10) :1017-1023 (2006)

Background Reference 03

Hillier, L.W., et al. Nature 434 (7034) :724-731 (2005)

Background Reference 04

Quesada, V., et al. Biochem. Biophys. Res. Commun. 314 (1) :54-62 (2004)

Other Product Names

Ubiquitin carboxyl-terminal hydrolase 40, Deubiquitinating enzyme 40, Ubiquitin thioesterase 40, Ubiquitin-specific-processing protease 40, USP40

Tested Applications

Protein ID

59803114

Physical Properties

Liquid

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