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MORC1 Antibody

Product Specifications

Background

This gene encodes the human homolog of mouse morc and like the mouse protein it is testis-specific. Mouse studies support a testis-specific function since only male knockout mice are infertile; infertility is the only apparent defect. These studies further support a role for this protein early in spermatogenesis, possibly by affecting entry into apoptosis because testis from knockout mice show greatly increased numbers of apoptotic cells.

NCBI Gene ID

27136

Swiss Prot

Q86VD1

Accession Number

Q86VD1

Host

Rabbit

Reactivity

Human

Immunogen

This MORC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 892-921 amino acids from the C-terminal region of human MORC1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

113 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

MORC1

NCBI Official Name

MORC family CW-type zinc finger protein 1

NCBI Organism

Homo sapiens

Background Reference 01

Rose, J. Phd, et al. Mol. Med. (2010) In press :

Background Reference 02

Inoue, N., et al. Cytogenet. Cell Genet. 90 (1-2), 123-125 (2000) :

Background Reference 03

Inoue, N., et al. Hum. Mol. Genet. 8 (7) :1201-1207 (1999)

Other Product Names

MORC family CW-type zinc finger protein 1, Cancer/testis antigen 33, CT33, MORC1 {ECO:0000312|EMBL:AAH503071}

Tested Applications

WB

Protein ID

269849621

Physical Properties

Liquid

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