PHF5A Antibody

Product Specifications

Background

This gene encodes a subunit of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP) . The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. The protein encoded by this gene contains a PHD-finger-like domain that is flanked by highly basic N- and C-termini. This protein belongs to the PHD-finger superfamily and may act as a chromatin-associated protein. This gene has several pseudogenes on different chromosomes.

NCBI Gene ID

84844

Swiss Prot

Q7RTV0

Accession Number

Q7RTV0

Host

Rabbit

Reactivity

Human

Immunogen

This PHF5A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-110 amino acids from the C-terminal region of human PHF5A.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

12 kDa

Fragment

Rabbit Ig

Symbol

PHF5A

NCBI Official Name

PHD finger-like domain-containing protein 5A

NCBI Organism

Homo sapiens

Background Reference 01

Kuwasako, K., et al. Proteins 71 (4) :1617-1636 (2008)

Background Reference 02

Will, C.L., et al. RNA 10 (6) :929-941 (2004)

Background Reference 03

Collins, J.E., et al. Genome Biol. (10), R84 (2004) :

Background Reference 04

Will, C.L., et al. EMBO J. 21 (18) :4978-4988 (2002)

Other Product Names

PHD finger-like domain-containing protein 5A, PHD finger-like domain protein 5A, Splicing factor 3B-associated 14 kDa protein, SF3b14b, PHF5A

Tested Applications

WB, Flow

Protein ID

46577625

Physical Properties

Liquid

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