BRD7 Antibody

Product Specifications

Background

This gene encodes a protein which is a member of the bromodomain-containing protein family. The product of this gene has been identified as a component of one form of the SWI/SNF chromatin remodeling complex, and as a protein which interacts with p53 and is required for p53-dependent oncogene-induced senescence which prevents tumor growth. Pseudogenes have been described on chromosomes 2, 3, 6, 13 and 14. Alternative splicing results in multiple transcript variants.

NCBI Gene ID

29117

Swiss Prot

Q9NPI1

Accession Number

Q9NPI1

Host

Rabbit

Reactivity

Mouse

Immunogen

This BRD7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 77-106 amino acids from the N-terminal region of human BRD7.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

74 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

BRD7

NCBI Official Name

Bromodomain-containing protein 7

NCBI Organism

Homo sapiens

Background Reference 01

Burrows, A.E., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (32) :14280-14285 (2010)

Background Reference 02

Drost, J., et al. Nat. Cell Biol. 12 (4) :380-389 (2010)

Background Reference 03

Kikuchi, M., et al. Biochim. Biophys. Acta 1793 (12) :1828-1836 (2009)

Background Reference 04

Kaeser, M.D., et al. J. Biol. Chem. 283 (47) :32254-32263 (2008)

Other Product Names

Bromodomain-containing protein 7, 75 kDa bromodomain protein, Protein CELTIX-1, BRD7, BP75, CELTIX1

Tested Applications

Protein ID

74734307

Physical Properties

Liquid

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