PHF17 Antibody
Product Specifications
Background
Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Transcriptional coactivator it may also promote acetylation of nucleosomal histone H4 by KAT5. Promotes apoptosis. May act as a renal tumor suppressor.
NCBI Gene ID
79960
Swiss Prot
Q6IE81
Accession Number
Q6IE81
Host
Rabbit
Reactivity
Human
Immunogen
This PHF17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-51 amino acids from the N-terminal region of human PHF17.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
96 kDa
Fragment
Rabbit Ig
Symbol
JADE1
NCBI Official Name
Protein Jade-1
NCBI Organism
Homo sapiens
Background Reference 01
Foy, R.L., et al. J. Biol. Chem. 283 (43) :28817-28826 (2008)
Background Reference 02
Chitalia, V.C., et al. Nat. Cell Biol. 10 (10) :1208-1216 (2008)
Background Reference 03
Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)
Background Reference 04
Lim, J., et al. Cell 125 (4) :801-814 (2006)
Other Product Names
Protein Jade-1, Jade family PHD finger protein 1, PHD finger protein 17, JADE1, KIAA1807, PHF17
Tested Applications
WB, IHC-P
Protein ID
74748786
Physical Properties
Liquid
Curated Selection
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