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RPL3 Antibody

Product Specifications

Background

Ribosomes, the complexes that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L3P family of ribosomal proteins and it is located in the cytoplasm. The protein can bind to the HIV-1 TAR mRNA, and it has been suggested that the protein contributes to tat-mediated transactivation. This gene is co-transcribed with several small nucleolar RNA genes, which are located in several of this gene's introns. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq].

NCBI Gene ID

6122

Swiss Prot

P39023

Accession Number

P39023

Host

Rabbit

Reactivity

Human

Immunogen

This RPL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 224-251 amino acids from the Central region of human RPL3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Monkey, Mouse, Pig, Rat, Yeast

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

46 kDa

Fragment

Rabbit Ig

Symbol

RPL3

NCBI Official Name

60S ribosomal protein L3

NCBI Organism

Homo sapiens

Background Reference 01

Russo, A., et al. Biochim. Biophys. Acta 1799 (5-6), 419-428 (2010) :

Background Reference 02

Rikova, K., et al. Cell 131 (6) :1190-1203 (2007)

Background Reference 03

Tu, L.C., et al. Mol. Cell Proteomics 6 (4) :575-588 (2007)

Background Reference 04

Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :

Other Product Names

60S ribosomal protein L3, HIV-1 TAR RNA-binding protein B, TARBP-B, RPL3

Tested Applications

WB, IHC-P

Protein ID

730565

Physical Properties

Liquid

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