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UPRT Antibody

Product Specifications

Background

This gene encodes uracil phosphoribosyltransferase, which catalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (UMP) . This reaction is an important part of nucleotide metabolism, specifically the pyrimidine salvage pathway. The enzyme localizes to the nucleus and cytoplasm. The protein is a potential target for rational design of drugs to treat parasitic infections and cancer.

NCBI Gene ID

139596

Swiss Prot

Q96BW1

Accession Number

Q96BW1

Host

Rabbit

Reactivity

Mouse

Immunogen

This UPRT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 204-233 amino acids from the C-terminal region of human UPRT.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Monkey

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

34 kDa

Fragment

Rabbit Ig

Symbol

UPRT

NCBI Official Name

Uracil phosphoribosyltransferase homolog

NCBI Organism

Homo sapiens

Background Reference 01

Zhao, F.J., et al. Prostate Cancer Prostatic Dis. 12 (2) :166-171 (2009)

Background Reference 02

Li, J., et al. J. Hum. Genet. 52 (5) :415-422 (2007)

Other Product Names

Uracil phosphoribosyltransferase homolog, UPRT

Tested Applications

WB, IHC-P

Protein ID

74751783

Physical Properties

Liquid

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