TRIM13 Antibody

Product Specifications

Background

This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This gene is located on chromosome 13 within the minimal deletion region for B-cell chronic lymphocytic leukemia. Multiple alternatively spliced transcript variants have been found for this gene.

NCBI Gene ID

10206

Swiss Prot

O60858

Accession Number

O60858

Host

Rabbit

Reactivity

Human

Immunogen

This TRIM13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 61-90 amino acids from the N-terminal region of human TRIM13.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

47 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

TRIM13

NCBI Official Name

E3 ubiquitin-protein ligase TRIM13

NCBI Organism

Homo sapiens

Background Reference 01

Lerner, M., et al. Mol. Biol. Cell 18 (5) :1670-1682 (2007)

Background Reference 02

Skoblov, M., et al. Biochem. Biophys. Res. Commun. 342 (3) :859-866 (2006)

Background Reference 03

Corcoran, M.M., et al. Genes Chromosomes Cancer 40 (4) :285-297 (2004)

Background Reference 04

Dunham, A., et al. Nature 428 (6982) :522-528 (2004)

Other Product Names

E3 ubiquitin-protein ligase TRIM13, 632-, B-cell chronic lymphocytic leukemia tumor suppressor Leu5, Leukemia-associated protein 5, Putative tumor suppressor RFP2, RING finger protein 77, Ret finger protein 2, Tripartite motif-containing protein 13, TRIM13, LEU5, RFP2, RNF77