RNF43 Antibody
Product Specifications
Background
RNF43 is a HAP95 (AKAP8L; MIM 609475) binding ubiquitin ligase that promotes cell growth and is upregulated in colon cancer (Yagyu et al., 2004 [PubMed 15492824]; Sugiura et al., 2008 [PubMed 18313049]) .
NCBI Gene ID
54894
Swiss Prot
Q68DV7
Accession Number
Q68DV7
Host
Rabbit
Reactivity
Human
Immunogen
This RNF43 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 543-572 amino acids from the C-terminal region of human RNF43.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
86 kDa
Fragment
Rabbit Ig
Symbol
RNF43
NCBI Official Name
E3 ubiquitin-protein ligase RNF43
NCBI Organism
Homo sapiens
Background Reference 01
Low, S.K., et al. PLoS ONE (7), E11824 (2010) :
Background Reference 02
Sugiura, T., et al. Exp. Cell Res. 314 (7) :1519-1528 (2008)
Background Reference 03
Uchida, N., et al. Clin. Cancer Res. 10 (24) :8577-8586 (2004)
Background Reference 04
Yagyu, R., et al. Int. J. Oncol. 25 (5) :1343-1348 (2004)
Other Product Names
E3 ubiquitin-protein ligase RNF43, 632-, RING finger protein 43, RNF43
Tested Applications
WB, IHC-P
Protein ID
74757361
Physical Properties
Liquid
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