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AMELX Antibody

Product Specifications

Background

This gene encodes a member of the amelogenin family of extracellular matrix proteins. Amelogenins are involved in biomineralization during tooth enamel development. Mutations in this gene cause X-linked amelogenesis imperfecta. Alternative splicing results in multiple transcript variants encoding different isoforms.

NCBI Gene ID

265

Swiss Prot

Q99217

Accession Number

Q99217

Host

Rabbit

Reactivity

Human

Immunogen

This AMELX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-46 amino acids from the N-terminal region of human AMELX.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

22 kDa

Fragment

Rabbit Ig

Symbol

AMELX

NCBI Official Name

Amelogenin, X isoform

NCBI Organism

Homo sapiens

Background Reference 01

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 02

Almqvist, S., et al.Mater Sci Mater Med 21 (3) :947-954 (2010)

Background Reference 03

Lee, S.K., et al. J. Dent. Res. 89 (1) :46-50 (2010)

Background Reference 04

Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)

Other Product Names

Amelogenin, X isoform, AMELX, AMG, AMGX

Tested Applications

WB, IHC-P, Flow

Protein ID

1168430

Physical Properties

Liquid

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