CAPN8 Antibody
Product Specifications
Background
Calcium-regulated non-lysosomal thiol-protease. Involved in membrane trafficking in the gastric surface mucus cells (pit cells) and may involve the membrane trafficking of mucus cells via interactions with coat protein. Proteolytically cleaves the beta-subunit of coatomer complex (By similarity) .
NCBI Gene ID
388743
Swiss Prot
A6NHC0
Accession Number
A6NHC0
Host
Rabbit
Reactivity
Human
Immunogen
This CAPN8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 290-318 amino acids from the Central region of human CAPN8.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
79 kDa
Fragment
Rabbit Ig
Symbol
CAPN8
NCBI Official Name
Calpain-8
NCBI Organism
Homo sapiens
Background Reference 01
Hata, S., et al. J. Biol. Chem. 282 (38) :27847-27856 (2007)
Background Reference 02
Oh, J.H., et al. Mamm. Genome 16 (12) :942-954 (2005)
Background Reference 03
Hata, S., et al. J. Mol. Evol. 53 (3) :191-203 (2001)
Background Reference 04
Huang, Y., et al. Trends Mol Med 7 (8) :355-362 (2001)
Other Product Names
Calpain-8, New calpain 2, nCL-2, Stomach-specific M-type calpain, CAPN8, NCL2
Tested Applications
WB, IHC-P
Physical Properties
Liquid
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