EIF2B5 Antibody

Product Specifications

Background

This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.

NCBI Gene ID

8893

Swiss Prot

Q13144

Accession Number

Q13144

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This EIF2B5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-65 amino acids from the N-terminal region of human EIF2B5.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

80 kDa

Fragment

Rabbit Ig

Symbol

EIF2B5

NCBI Official Name

Translation initiation factor eIF-2B subunit epsilon

NCBI Organism

Homo sapiens

Background Reference 01

Van der Lei, H.D., et al. Neurology 75 (17) :1555-1559 (2010)

Background Reference 02

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 03

Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)

Background Reference 04

Pronk, J., et al. Mult. Scler. 14 (8) :1123-1126 (2008)

Other Product Names

Translation initiation factor eIF-2B subunit epsilon, eIF-2B GDP-GTP exchange factor subunit epsilon, EIF2B5, EIF2BE

Tested Applications

WB, IHC-P

Protein ID

160359049

Physical Properties

Liquid

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