Mouse BID Antibody

Product Specifications

Background

Bid is a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. Bid is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8) ; CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release.

NCBI Gene ID

12122

Swiss Prot

P70444

Accession Number

P70444

Host

Rabbit

Reactivity

Mouse

Immunogen

This mouse BID antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-68 amino acids from mouse BID.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Obesity

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

22 kDa

Fragment

Rabbit Ig

Symbol

Bid

NCBI Official Name

BH3-interacting domain death agonist

NCBI Organism

Mus musculus

Background Reference 01

Ziporen, L., J. Immunol. 182 (1), 515-521 (2009)

Background Reference 02

Kaufmann, T., Immunity 30 (1), 56-66 (2009)

Background Reference 03

Mandal, M., Proc. Natl. Acad. Sci. U.S.A. 105 (52), 20840-20845 (2008)

Other Product Names

BH3-interacting domain death agonist, p22 BID, BID, BH3-interacting domain death agonist p15, p15 BID, BH3-interacting domain death agonist p13, p13 BID, BH3-interacting domain death agonist p11, p11 BID, Bid