MPP3 Antibody
Product Specifications
Background
This gene product is a member of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs) . MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. This protein contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction. Alternatively spliced transcript variants have been identified. One transcript variant is experimentally supported, but it doesn't encode a protein.
NCBI Gene ID
4356
Swiss Prot
Q13368
Accession Number
Q13368
Host
Rabbit
Reactivity
Human
Immunogen
This MPP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 406-434 amino acids from the C-terminal region of human MPP3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
66 kDa
Fragment
Rabbit Ig
Symbol
MPP3
NCBI Official Name
MAGUK p55 subfamily member 3
NCBI Organism
Homo sapiens
Background Reference 01
Qin, L., et al. Zhonghua Gan Zang Bing Za Zhi 15 (7) :509-512 (2007)
Background Reference 02
Kantardzhieva, A., et al. FEBS J. 273 (6) :1152-1165 (2006)
Background Reference 03
Stelzl, U., et al. Cell 122 (6) :957-968 (2005)
Background Reference 04
Fukuhara, H., et al. Oncogene 22 (40) :6160-6165 (2003)
Other Product Names
MAGUK p55 subfamily member 3, Discs large homolog 3, Protein MPP3, MPP3, DLG3
Tested Applications
WB, IF, Flow
Protein ID
150421601
Physical Properties
Liquid
Curated Selection
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