MPO Antibody

Product Specifications

Background

Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of netrophils. [provided by RefSeq].

NCBI Gene ID

4353

Swiss Prot

P05164

Accession Number

P05164

Host

Rabbit

Reactivity

Human

Immunogen

This MPO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 548-575 amino acids from the C-terminal region of human MPO.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Immunology, Obesity

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

84 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

MPO

NCBI Official Name

Myeloperoxidase

NCBI Organism

Homo sapiens

Background Reference 01

Banerjee, M., et al. Toxicol. Appl. Pharmacol. 249 (1) :47-54 (2010)

Background Reference 02

Shimada, M., et al. Hum. Genet. 128 (4) :433-441 (2010)

Background Reference 03

Nahon, P., et al. Antioxid. Redox Signal. (2010) In press :

Background Reference 04

Wang, Y., et al. J. Huazhong Univ. Sci. Technol. Med. Sci. 30 (4) :437-442 (2010)

Other Product Names

Myeloperoxidase, MPO, Myeloperoxidase, 89 kDa myeloperoxidase, 84 kDa myeloperoxidase, Myeloperoxidase light chain, Myeloperoxidase heavy chain, MPO

Tested Applications

Protein ID

129825

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

RC215233L2 10 µg

HDAC7 (NM_015401) Human Tagged Lenti ORF Clone

Ask

View Details

TP762010 50 µg

DPPA2 (NM_138815) Human Recombinant Protein

Ask

View Details

MP1008X Each

Magic™ Membrane Protein Human PDGFD (Platelet derived growth factor D) for Antibody Discovery

Ask

View Details

E28PN1988 100 µL

TEFF2 Rabbit Polyclonal Antibody

Ask

View Details

NBP3-24114JF525 0.1 mL

Mouse Monoclonal S100G Antibody (S100G/7516) [Janelia Fluor 525]

Ask

View Details