ANKRD6 Antibody

Product Specifications

Background

ANKRD6 recruits CKI-epsilon to the beta-catenin degradation complex that consists of AXN1 or AXN2 and GSK3-beta and allows efficient phosphorylation of beta-catenin, thereby inhibiting beta-catenin/Tcf signals (By similarity) .

NCBI Gene ID

22881

Swiss Prot

Q9Y2G4

Accession Number

Q9Y2G4

Host

Rabbit

Reactivity

Human

Immunogen

This ANKRD6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 314-343 amino acids from the Central region of human ANKRD6.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

80 kDa

Fragment

Rabbit Ig

Symbol

ANKRD6

NCBI Official Name

Ankyrin repeat domain-containing protein 6

NCBI Organism

Homo sapiens

Background Reference 01

Haribaskar, R., et al. Biochem. Biophys. Res. Commun. 387 (1) :212-217 (2009)

Background Reference 02

Miyasaka, K.Y., et al. Proc. Natl. Acad. Sci. U.S.A. 104 (27) :11274-11279 (2007)

Background Reference 03

Schwarz-Romond, T., et al. Genes Dev. 16 (16) :2073-2084 (2002)

Background Reference 04

Tissir, F., et al. Dev. Dyn. 224 (4) :465-469 (2002)

Other Product Names

Ankyrin repeat domain-containing protein 6, Diversin, ANKRD6, KIAA0957

Tested Applications

WB, IHC-P

Protein ID

327478595

Physical Properties

Liquid

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