TBCA Antibody

Product Specifications

Background

The product of this gene is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. This gene encodes chaperonin cofactor A.

NCBI Gene ID

6902

Swiss Prot

O75347

Accession Number

O75347

Host

Rabbit

Reactivity

Human

Immunogen

This TBCA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-44 amino acids from the N-terminal region of human TBCA.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rb

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

13 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

TBCA

NCBI Official Name

Tubulin-specific chaperone A

NCBI Organism

Homo sapiens

Background Reference 01

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 02

Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34 (5) :800-812 (2010)

Background Reference 03

Bruneel, A., et al. Proteomics 5 (15) :3876-3884 (2005)

Background Reference 04

Nolasco, S., et al. FEBS Lett. 579 (17) :3515-3524 (2005)

Other Product Names

Tubulin-specific chaperone A, TCP1-chaperonin cofactor A, Tubulin-folding cofactor A, CFA, TBCA

Tested Applications

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

RQ7644 100 µg

SGTB Antibody / SGT2

Ask

View Details

ABF9147 100 µg

OTUB2 Antibody

Ask

View Details

DD61113 1 Each

Micropipette Acura 835 1-10 uL Socorex

Ask

View Details

GTR15096437 1 Vial

Lentiviral human CANT1 shRNA (UAS) - Lentiviral human CANT1 shRNA (UAS) (25)

Ask

View Details