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CHTF18 Antibody

Product Specifications

Background

CHTF18, CHTF8 (MIM 613202), and DCC1 (DSCC1; MIM 613203) are components of an alternative replication factor C (RFC) (see MIM 600404) complex that loads PCNA (MIM 176740) onto DNA during S phase of the cell cycle (Merkle et al., 2003 [PubMed 12766176]; Bermudez et al., 2003 [PubMed 12930902]) .

NCBI Gene ID

63922

Swiss Prot

Q8WVB6

Accession Number

Q8WVB6

Host

Rabbit

Reactivity

Human

Immunogen

This CHTF18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 914-943 amino acids from the C-terminal region of human CHTF18.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

107 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

CHTF18

NCBI Official Name

Chromosome transmission fidelity protein 18 homolog

NCBI Organism

Homo sapiens

Background Reference 01

Murakami, T., et al. J. Biol. Chem. 285 (45) :34608-34615 (2010)

Background Reference 02

Farina, A., et al. J. Biol. Chem. 283 (30) :20925-20936 (2008)

Background Reference 03

Shiomi, Y., et al. J. Biol. Chem. 282 (29) :20906-20914 (2007)

Background Reference 04

Matsuoka, S., et al. Science 316 (5828) :1160-1166 (2007)

Other Product Names

Chromosome transmission fidelity protein 18 homolog, hCTF18, CHL12, CHTF18, C16orf41, CTF18

Tested Applications

WB

Protein ID

74751544

Physical Properties

Liquid

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