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GK Antibody

Product Specifications

Background

The product of this gene belongs to the FGGY kinase family of proteins and encodes glycerol kinase. Glycerol kinase is a key enzyme in the regulation of glycerol uptake and metabolism. It catalyzes the phosphorylation of glycerol by ATP, yielding ADP and glycerol-3-phosphate. Defects in this gene are the cause of glycerol kinase deficiency (GKD) . Alternatively spliced transcript variants encoding different isoforms have been identified.

NCBI Gene ID

2710

Swiss Prot

P32189

Accession Number

P32189

Host

Rabbit

Reactivity

Human

Immunogen

This GK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-51 amino acids from the N-terminal region of human GK.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=56-739

Calculated Molecular Weight

61 kDa

Fragment

Rabbit Ig

Symbol

GK

NCBI Official Name

Glycerol kinase

NCBI Organism

Homo sapiens

Background Reference 01

Lu, Y., et al. J. Lipid Res. 49 (12) :2582-2589 (2008)

Background Reference 02

Zhang, Y.H., et al. Pediatr. Res. 59 (4 PT 1), 590-592 (2006) :

Background Reference 03

Ohira, R.H., et al. Biochem. Biophys. Res. Commun. 331 (1) :239-246 (2005)

Background Reference 04

Stepanian, S.V., et al. Mol. Genet. Metab. 80 (4) :412-418 (2003)

Other Product Names

Glycerol kinase, GK, Glycerokinase, ATP:glycerol 3-phosphotransferase, GK

Tested Applications

WB, IHC-P

Protein ID

205830913

Physical Properties

Liquid

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