SERPINE1 Antibody

Product Specifications

Background

This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

5054

Swiss Prot

P05121

Accession Number

P05121

Host

Rabbit

Reactivity

Human

Immunogen

This SERPINE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-216 amino acids from the Central region of human SERPINE1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Immunology, Obesity

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

45 kDa

Fragment

Rabbit Ig

Symbol

SERPINE1

NCBI Official Name

Plasminogen activator inhibitor 1

NCBI Organism

Homo sapiens

Background Reference 01

Ma, Z., et al. Biochem. Biophys. Res. Commun. 400 (4) :569-574 (2010)

Background Reference 02

Ince, D.A., et al. Genet Test Mol Biomarkers 14 (5) :643-647 (2010)

Background Reference 03

Bern, M.M., et al. Clin. Appl. Thromb. Hemost. 16 (5) :574-578 (2010)

Background Reference 04

Markl, B., et al.Surg Oncol 102 (3) :235-241 (2010)

Other Product Names

Plasminogen activator inhibitor 1, PAI, PAI-1, Endothelial plasminogen activator inhibitor, Serpin E1, SERPINE1, PAI1, PLANH1

Tested Applications

WB, Flow

Protein ID

129576

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

MBS3905533-01 0.01 mg

Rabbit anti-DOCK2 Antibody, Affinity Purified

Ask

View Details

MBS3905533-02 0.1 mg

Rabbit anti-DOCK2 Antibody, Affinity Purified

Ask

View Details

MBS3905533-03 5x 0.01 mg

Rabbit anti-DOCK2 Antibody, Affinity Purified

Ask

View Details

MBS3905533-04 5x 0.1 mg

Rabbit anti-DOCK2 Antibody, Affinity Purified

Ask

View Details

PAV8237 100 μL

Rabbit Anti-IMP3 Polyclonal Antibody

Ask

View Details

131779-ML490 100 µL

PRKAB1 (5'-AMP-activated Protein Kinase Subunit beta-1, AMPK Subunit beta-1, AMPKb, AMPK, MGC17785) (MaxLight 490)

Ask

View Details