HMFG Antibody

Product Specifications

Background

HMFG plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization (By similarity) . Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. Binds specifically to rotavirus and inhibits its replication. Medin is the main constituent of aortic medial amyloid.

NCBI Gene ID

4240

Swiss Prot

Q08431

Accession Number

Q08431

Host

Rabbit

Reactivity

Human

Immunogen

This HMFG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 316-345 amino acids from the C-terminal region of human HMFG.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Cell Cycle, Obesity

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

43 kDa

Fragment

Rabbit Ig

Symbol

MFGE8

NCBI Official Name

Lactadherin

NCBI Organism

Homo sapiens

Background Reference 01

Yamaguchi, H., et al. Eur. J. Immunol. 40 (6) :1778-1785 (2010)

Background Reference 02

Wheeler, H.E., et al. PLoS Genet. (10), E1000685 (2009) :

Background Reference 03

Hu, C.Y., et al. Lupus 18 (8) :676-681 (2009)

Background Reference 04

Fu, Z., et al. Circ. Res. 104 (12) :1337-1346 (2009)

Other Product Names

Lactadherin, Breast epithelial antigen BA46, HMFG, MFGM, Milk fat globule-EGF factor 8, MFG-E8, SED1, Lactadherin short form, Medin, MFGE8

Tested Applications

WB, Flow

Protein ID

2506380

Physical Properties

Liquid

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