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CBR3 Antibody

Product Specifications

Background

Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. The enzyme is classified as a monomeric NADPH-dependent oxidoreductase. CBR3 contains three exons spanning 11.2 kilobases and is closely linked to another carbonyl reductase gene - CBR1.

NCBI Gene ID

874

Swiss Prot

O75828

Accession Number

O75828

Host

Rabbit

Reactivity

Human

Immunogen

This CBR3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-224 amino acids from the C-terminal region of human CBR3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

31 kDa

Fragment

Rabbit Ig

Symbol

CBR3

NCBI Official Name

Carbonyl reductase [NADPH] 3

NCBI Organism

Homo sapiens

Background Reference 01

Guey, L.T., et al. Eur. Urol. 57 (2) :283-292 (2010)

Background Reference 02

Hosgood, H.D. III, et al. Respir Med 103 (12) :1866-1870 (2009)

Background Reference 03

Zhang, J., et al. Pharm. Res. 26 (9) :2209-2215 (2009)

Background Reference 04

Choi, J.Y., et al. Clin. Cancer Res. 15 (16) :5258-5266 (2009)

Other Product Names

Carbonyl reductase [NADPH] 3, NADPH-dependent carbonyl reductase 3, CBR3

Tested Applications

WB, Flow

Physical Properties

Liquid

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