POFUT2 Antibody

Product Specifications

Background

Fucose is typically found as a terminal modification of branched chain glycoconjugates, but it also exists in direct O-linkage to serine or threonine residues within cystine knot motifs in epidermal growth factor (EGF; MIM 131530) -like repeats or thrombospondin (THBS; see MIM 188060) type-1 repeats. POFUT2 is an O-fucosyltransferase that use THBS type-1 repeats as substrates (Luo et al., 2006 [PubMed 16464857]) .

NCBI Gene ID

23275

Swiss Prot

Q9Y2G5

Accession Number

Q9Y2G5

Host

Rabbit

Reactivity

Human

Immunogen

This POFUT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-257 amino acids from the Central region of human POFUT2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

50 kDa

Fragment

Rabbit Ig

Symbol

POFUT2

NCBI Official Name

GDP-fucose protein O-fucosyltransferase 2

NCBI Organism

Homo sapiens

Background Reference 01

Feng, T., et al. Hum. Genet. 128 (3) :269-280 (2010)

Background Reference 02

Luo, Y., et al. J. Biol. Chem. 281 (14) :9385-9392 (2006)

Background Reference 03

Luo, Y., et al. J. Biol. Chem. 281 (14) :9393-9399 (2006)

Background Reference 04

Menzel, O., et al. Genomics 84 (2) :320-330 (2004)

Other Product Names

GDP-fucose protein O-fucosyltransferase 2, Peptide-O-fucosyltransferase 2, O-FucT-2, POFUT2, C21orf80, FUT13, KIAA0958

Tested Applications

WB, IHC-P

Protein ID

59803123

Physical Properties

Liquid

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