DOC2A Antibody

Product Specifications

Background

There are at least two protein isoforms of the Double C2 protein, namely alpha (DOC2A) and beta (DOC2B), which contain two C2-like domains. DOC2A and DOC2B are encoded by different genes; these genes are at times confused with the unrelated DAB2 gene which was initially named DOC-2. DOC2A is mainly expressed in brain and is suggested to be involved in Ca (2+) -dependent neurotransmitter release.

NCBI Gene ID

8448

Swiss Prot

Q14183

Accession Number

Q14183

Host

Rabbit

Reactivity

Human

Immunogen

This DOC2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 277-306 amino acids from the Central region of human DOC2A.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

44 kDa

Fragment

Rabbit Ig

Symbol

DOC2A

NCBI Official Name

Double C2-like domain-containing protein alpha

NCBI Organism

Homo sapiens

Background Reference 01

Shimada, M., et al. Hum. Genet. 128 (4) :433-441 (2010)

Background Reference 02

Glessner, J.T., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (23) :10584-10589 (2010)

Background Reference 03

Guilmatre, A., et al. Arch. Gen. Psychiatry 66 (9) :947-956 (2009)

Background Reference 04

Kumar, R.A., et al. PLoS ONE (2), E4582 (2009) :

Other Product Names

Double C2-like domain-containing protein alpha, Doc2, Doc2-alpha, DOC2A

Tested Applications

WB, IHC-P, Flow

Protein ID

150421541

Physical Properties

Liquid

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