UNC45A Antibody

Product Specifications

Background

UNC45A plays a role in cell proliferation and myoblast fusion, binds progesterone receptor (PGR; MIM 607311) and HSP90 (HSPCA; MIM 140571), and acts as a regulator of the progesterone receptor chaperoning pathway (Price et al., 2002 [PubMed 12356907]; Chadli et al., 2006 [PubMed 16478993]) .

NCBI Gene ID

55898

Swiss Prot

Q9H3U1

Accession Number

Q9H3U1

Host

Rabbit

Reactivity

Human

Immunogen

This UNC45A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 146-174 amino acids from the N-terminal region of human UNC45A.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

103 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

UNC45A

NCBI Official Name

Protein unc-45 homolog A

NCBI Organism

Homo sapiens

Background Reference 01

Chadli, A., et al. J. Biol. Chem. 283 (15) :9509-9512 (2008)

Background Reference 02

Bazzaro, M., et al. Am. J. Pathol. 171 (5) :1640-1649 (2007)

Background Reference 03

Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :

Background Reference 04

Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

Other Product Names

Protein unc-45 homolog A, Unc-45A, GCUNC-45, Smooth muscle cell-associated protein 1, SMAP-1, UNC45A, SMAP1

Tested Applications

Protein ID

74761419

Physical Properties

Liquid

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