RFX2 Antibody
Product Specifications
Background
This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for this gene, and both variants utilize alternative polyadenylation sites.
NCBI Gene ID
5990
Swiss Prot
P48378
Accession Number
P48378
Host
Rabbit
Reactivity
Human
Immunogen
This RFX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 669-698 amino acids from the C-terminal region of human RFX2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
80 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
RFX2
NCBI Official Name
DNA-binding protein RFX2
NCBI Organism
Homo sapiens
Background Reference 01
Purvis, T.L., et al. Gene 460 (1-2), 20-29 (2010) :
Background Reference 02
Bailey, S.D., et al. Diabetes Care (2010) In press :
Background Reference 03
Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)
Background Reference 04
Horvath, G.C., et al. Biol. Reprod. 71 (5) :1551-1559 (2004)
Other Product Names
DNA-binding protein RFX2, Regulatory factor X 2, RFX2
Tested Applications
WB
Protein ID
254763325
Physical Properties
Liquid
Curated Selection
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